From Jacksonville Area:

Take I-10 West
Take Exit # 343 /Baldwin/Starke onto US-301 South for 13.3 miles
Continue to follow US-301 South for 23.7 miles
Bear Right on SR-24 West for 13.2 miles
Continue on SE Williston Rd [SR-331 S] for 1.8 miles
Turn Right on SE 16th Ave [SR-226] for 0.5 miles
Turn Right on S Main St [SR-329 N] for 0.2 miles
Arrive at 1315 S Main St on the Right

Note: Some Towns on US 301 vigorously enforce speeding laws and do speed traps 24/7. Hampton, Lawtey and Waldo have been designated speed traps by Triple A. Adjust your speed accordingly when driving through these areas. Do not exceed posted speed limits!

From Orlando Area:

Start off taking Florida Turnpike North [Portions Toll]
Exit onto I-75 North for 56.1 miles
Take Exit # 382 [SR-331] towards Gainesville
Turn Left on SW Williston Rd [SR-121 North]
Continue on SW Williston Rd [SR-331 North] for 3.6 miles
Turn Left on SE 16th Ave [SR-226] for 0.6 miles
Turn Right on S Main St [SR-329 N] for 0.2 miles
Arrive at 1315 S Main St on the Right

Area Map [Click To Enlarge]

From Tallahassee Area:

Take I-10 East for 87.6 miles
Take Exit # 296A onto I-75 South for 50.9 miles
Take Exit # 384 towards Gainesville
Turn Left on SW Archer Rd [SR-24 East] for 2.3 miles
Continue on SW 16th Ave [SR-226 West] for 1.7 miles
Turn Left on S Main St [SR-329 N] for 0.2 miles
Arrive at 1315 S Main St on the right

From Tampa/St. Petersburg Areas:

Take I-275 North
Exit onto I-75 North and go 110.0 miles
Take Exit # 382 [SR-331] towards Gainesville
Turn Left on SW Williston Rd [SR-121 North]
Continue on SW Williston Rd [SR-331 North] for 3.6 miles
Turn Left on SE 16th Ave [SR-226] for 0.6 miles
Turn Right on S Main St [SR-329 N] for 0.2 miles
Arrive at 1315 S Main St on the Right

Venue Parking:

Backstage Lounge has ample free on-site parking.